If you've used Google Maps API to put a map on your site the javascript work you need to do can get quite hairy. GMapEZ puts an end to that. With GMapEZ, controlling google map on your site is as easy as writing HTML. I'm really impressed.
However, the usage in the grand scheme of things has to be taken with a pinch of salt. If you do want a Google Map on your site and do stuff with it, perhaps GMapEZ is not for you unless you want quick results. Simplifying APIs or other convenient libs are really only useful if it's not important. If it is important to you, in most cases you'll have to get ready to roll up your sleeves and get in there and do it yourself. GMapEZ does add more HTTP download for the user and additional javascript rendering time as well. So, if you have 1,000 users a day to view your Google Map app the time you save with being lazy with GMapEZ is paid by your users having to wait a long time extra for the overhead if you sum it all up.
But, like I said, if you think the Google Map API is too complicated sometimes then GMapEZ is definitely worth considering.
UPDATE
This tool looks really hot too. Worth remembering.